2026 NFL Preseason Odds Week 1: Lines, Spreads For All 16 Games

It’s almost impossible to accurately wager on the NFL preseason, considering fans have no idea which players will take the field. But that doesn’t mean it’s not worth a try. Here are the lines for every preseason Week 1 matchup at DraftKings Sportsbook as of Aug. 13. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. THURSDAY, AUG. 13 Packers @ Steelers Spread: Packers -2.5Moneyline: Packers -148, Packers +124O/U: 40.5 Lions @ Bengals Spread: Bengals -7Moneyline: Bengals -265, Lions +215O/U: 37.5 Colts @ Patriots Spread: Colts -3Moneyline: Colts -155, Colts +130O/U: 37.5 Chargers @ Texans Spread: Chargers -1.5Moneyline: Chargers -120, Chargers +100O/U: 36.5 Cardinals @ Raiders Spread: Raiders -2.5Moneyline: Raiders -142, Cardinals +120O/U: 42.5 Titans @ 49ers Spread: Titans -6Moneyline: Titans -238, 49ers +195O/U: 39.5 FRIDAY, AUG. 14 Dolphins @ Commanders Spread: Dolphins -3.5Moneyline: Dolphins -166, Commanders +140O/U: 35.5 Buccaneers @ Jets Spread: Jets -6Moneyline: Jets -265, Buccaneers +215O/U: 35.5 Broncos @ Falcons Spread: Broncos -4.5Moneyline: Broncos -198, Falcons +164O/U: 39.5 SATURDAY, AUG. 15 Panthers @ Bills Spread: Bills -3Moneyline: Bills -162, Bills +136O/U: 38.5 Vikings @ Giants Spread: Vikings -2.5Moneyline: Vikings -130, Giants +110O/U: 41.5 Browns @ Bears Spread: Browns -3Moneyline: Browns -185, Bears +154O/U: 40.5 Jaguars @ Saints Spread: Saints -1.5Moneyline: Saints -130, Jaguars +110O/U: 35.5 Rams @ Chiefs Spread: Chiefs -2.5Moneyline: Chiefs -142, Rams +120O/U: 36.5 Eagles @ Ravens Spread: Eagles -3.5Moneyline: Eagles -185, Ravens +154O/U: 37.5 Cowboys @ Seahawks Spread: Seahawks -3Moneyline: Seahawks -155, Cowboys +130O/U: 39.5