2026 NFL Preseason Odds Week 2: Spreads, Lines For All 16 Games

Books and bettors are back for Week 2 of the NFL preseason. Let’s check out the odds for each game at DraftKings Sportsbook as of Aug. 21. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. Thursday, Aug. 20 Raiders 22, Texans 20 Spread: Texans -1.5 (LV covers)O/U: 38.5 (Over hits) 49ers 41, Chargers 17 Spread: 49ers -1.5 (SF covers)O/U: 38.5 (Over hits) Friday, Aug. 21 Jets @ Steelers Spread: Jets -1.5Moneyline: Jets -122, Steelers +102O/U: 37.5 Panthers @ Jaguars Spread: Jaguars -1.5Moneyline: Jaguars -122, Panthers +102O/U: 37.5 Packers @ Broncos Spread: Broncos -6Moneyline: Broncos -245, Packers +200O/U: 41.5 Saturday, Aug. 22 Commanders @ Lions Spread: Lions -1.5Moneyline: Lions -130, Commanders +110O/U: 36.5 Bills @ Browns Spread: Browns -3Moneyline: Browns -155, Bills +130O/U: 36.5 Ravens @ Vikings Spread: Vikings -3.5Moneyline: Vikings -166, Ravens +140O/U: 36.5 Falcons @ Colts Spread: Colts -3.5Moneyline: Colts -175, Falcons +145O/U: 36.5 Saints @ Rams Spread: Saints -1.5Moneyline: Saints -130, Rams +110O/U: 37.5 Giants @ Dolphins Spread: Giants -3Moneyline: Giants -162, Dolphins +136O/U: 36.5 Bears @ Bengals Spread: Bears -1.5Moneyline: Bears -125, Bengals +105O/U: 36.5 Eagles @ Patriots Spread: Eagles -1.5Moneyline: Eagles -130, Patriots +110O/U: 36.5 Chiefs @ Buccaneers Spread: Buccaneers -5.5Moneyline: Buccaneers -230, Chiefs +190O/U: 37.5 Cowboys @ Cardinals Spread: Cardinals -1.5Moneyline: Cardinals -118, Cowboys -102O/U: 37.5 Sunday, Aug. 23 Seahawks @ Titans Spread: Titans -4.5Moneyline: Titans -218, Seahawks +180O/U: 38.5